Henoch-Schonlein Purpura (HSP)
Definition
Epidemiology
Clinical Features
Management
Prognosis
Source
Toronto Notes 2012
- Vasculitis of small vessels
Epidemiology
- Most common vasculitis of childhood
- Peak incidence 4-10 yrs, M:F = 2:1
- Recurrence in about one third of patients
- Often have history of URTI 1-3 wks before onset of symptoms
Clinical Features
- Triad:
- Purpura
- Arthritis
- Abdo pain
- Renal: IgA nephropathy, haematuria, proteinuria, hypertension, renal failure in <5%
Management
- Symptomatic, corticosteroids may relieve abdominal pain
- Monitor for renal disease, may develop late
- Immunosuppressive therapy for severe renal disease
Prognosis
- Self-limited disease in 90%
Source
Toronto Notes 2012