Drugs in Pregnancy
Foetal lung maturity
Atonic uterus
IOL
Hyperemesis Gravidarum
Ectopic pregnancy/ medical abortion
GBS prophylaxis
Infections
Rh negative mothers
GDM
Analgesics
Contraindications!!!
Weigh risks vs benefits
Source
Toronto Notes 2010
- Bethametasone valerate (Celestone)
- Dexamethasone
Atonic uterus
- Carbaprost (Hemabate)
- Methyergonavine (Ergotamine)
- Oxytocin (Pitocin)
IOL
- Dinoprostone (Cervidil - PGE2 thread)
- Oxytocin (Pitocin)
- PGE2 gel (Prostin)
Hyperemesis Gravidarum
- Doxylamine succinate (Diclectin)
Ectopic pregnancy/ medical abortion
- Methotrexate
- Misoprostol (Cytotec) - also for PPH and NSAID induced ulcer
GBS prophylaxis
- Benzylpenicillin aka penicillin G
- Ampicillin
- Clindamycin
- Erythromycin
Infections
- Cephalosporins
- Ampicillin
- Asymptomatic UTI: Augmentin
- Pyelonephritis: Cephalosporin/ Augmentin
- Toxoplasmosis: Pyrimethamine + Sulfadiazine + Folate
- HSV/ VZV: Aciclovir
Rh negative mothers
- Rh IgG (Rhogam)
GDM
- Metformin
- Gilbenclamide
- Insulin
Analgesics
- Paracetamol
Contraindications!!!
- ACEI
- Tetracyclines
- Retinoids (Accutane)
- Diethylstilbestrol (DES)
- Misoprostol
- Chloramphenicol
Weigh risks vs benefits
- Anticonvulsants
- Lithium
- Warfarin
Source
Toronto Notes 2010