Transient Tachypnoea of Newborn (TTN)
Definition
Pathophysiology
Risk Factors
Clinical Features
Investigations
Treatment
Prognosis
Source
Toronto Notes 2012
- AKA "wet lung syndrome" and RDS type II
Pathophysiology
- Delayed resorption of lung fluid --> accumulation of fluid in peribronchial lymphatics and vascular spaces --> ↑RR
Risk Factors
- Full term or near-term infant
- No labour/short labour (hypothesized lack of catecholamine release)
- C-section (lungs are not compressed during passage through pelvic floor)
- Diabetic mother/gestational weight >4500 g
- Maternal asthma
- Male
Clinical Features
- Mild respiratory distress
- Usually resolves in 24-72 h
Investigations
- CXR: fluid in fissures, increased vascularity, slight cardiomegaly
Treatment
- Supportive: 0 2, careful fluid administration, may use CPAP
Prognosis
- Full recovery expected within 2-5 d
- Children with TTN may be at increased risk of developing wheezing syndromes (such as asthma) in childhood
Source
Toronto Notes 2012