Squamous Cell Carcinoma
- second most common skin cancers
- occurs most commonly on chronically sun exposed areas (mainly head and hands)
- has potential to mets, significant mortality
- Risk factors: fair skin, excessive sun exposure, present and past, FHx, immunosuppression, chronic wounds (marjolin ulcer - ulcerating SCC growing within chronically inflammed/ traumatised wound), organ Tx, smoking (SCC lip)
- SCC: scaly, crusty
subtypes
- keratoacanthoma - nodular with keratin plug
- bowen’s disease (insitu SCC)
- occurs most commonly on chronically sun exposed areas (mainly head and hands)
- has potential to mets, significant mortality
- Risk factors: fair skin, excessive sun exposure, present and past, FHx, immunosuppression, chronic wounds (marjolin ulcer - ulcerating SCC growing within chronically inflammed/ traumatised wound), organ Tx, smoking (SCC lip)
- SCC: scaly, crusty
subtypes
- keratoacanthoma - nodular with keratin plug
- bowen’s disease (insitu SCC)
Management
- Excision and if insitu, has options of curettage, imiquimod, flurouracil-5, liquid nitrogen as well)
- high risk (lip, ear, rapidly growing, poorly differentiated, vascular or perineural invasion)
- check site and regional nodes
- skin check for other skin cancers
- 3-6mo regular follow up
Source
OHCS 8th edn 2009
Dr Clark 2014
DermnetNZ
- Excision and if insitu, has options of curettage, imiquimod, flurouracil-5, liquid nitrogen as well)
- high risk (lip, ear, rapidly growing, poorly differentiated, vascular or perineural invasion)
- check site and regional nodes
- skin check for other skin cancers
- 3-6mo regular follow up
Source
OHCS 8th edn 2009
Dr Clark 2014
DermnetNZ